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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C29101
http://purl.obolibrary.org/obo/NCIT_C29101
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|---|---|
| Preferred Name | Hydroxychloroquine Sulfate |
| Definitions |
A synthetic derivative of quinolyl with chemotherapeutic and antibiotic properties, Hydroxychloroquine Sulfate acts against erythrocytic malarial parasites (Plasmodium vivax, ovale, and malariae) by concentrating in food vacuoles. It inhibits plasmodial heme polymerase and acts through other unknown mechanisms. Hydroxychloroquine also has anti-inflammatory properties and is used in the treatment of rheumatoid arthritis and lupus erythematosus. (NCI04)
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A synthetic derivative of quinolyl with chemotherapeutic and antibiotic properties, Hydroxychloroquine Sulfate acts against erythrocytic malarial parasites (Plasmodium vivax, ovale, and malariae) by concentrating in food vacuoles. It inhibits plasmodial heme polymerase and acts through other unknown mechanisms. Hydroxychloroquine also has anti-inflammatory properties and is used in the treatment of rheumatoid arthritis and lupus erythematosus. (NCI04) |
|---|---|
| label | Hydroxychloroquine Sulfate
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| prefLabel | Hydroxychloroquine Sulfate
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| Has_Free_Acid_Or_Base_Form | |
| Legacy Concept Name | Hydroxychloroquine_Sulfate
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| in_subset | |
| Preferred_Name | Hydroxychloroquine Sulfate
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| Chemical_Formula | C18H26ClN3O.H2SO4
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| Display_Name | Hydroxychloroquine Sulfate
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| PDQ_Open_Trial_Search_ID | 801639
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| UMLS_CUI | C0596007
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| FDA_UNII_Code | 8Q2869CNVH
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| prefixIRI | NCIT:C29101
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| NCI_Drug_Dictionary_ID | 801639
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| Contributing_Source |
CTRP
FDA
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| subClassOf | |
| code | C29101
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| type | |
| NSC Number | 4375
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| PDQ_Closed_Trial_Search_ID | 801639
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| Semantic_Type | Pharmacologic Substance
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| CAS_Registry | 747-36-4
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| Delete | Subject | Author | Type | Created |
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