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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C28955
http://purl.obolibrary.org/obo/NCIT_C28955
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|---|---|
| Preferred Name | Carboxyphthalato-1,2-diaminocyclohexaneplatinum |
| Definitions |
A second-generation platinum analog with potential antineoplastic activity. Carboxyphthalato-1,2-diaminocyclohexaneplatinum alkylates DNA at the N-7 position of guanine, thereby producing DNA interstrand crosslinks and DNA strand breaks, and inhibiting DNA replication. (NCI04)
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A second-generation platinum analog with potential antineoplastic activity. Carboxyphthalato-1,2-diaminocyclohexaneplatinum alkylates DNA at the N-7 position of guanine, thereby producing DNA interstrand crosslinks and DNA strand breaks, and inhibiting DNA replication. (NCI04) |
|---|---|
| prefLabel | Carboxyphthalato-1,2-diaminocyclohexaneplatinum
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| label | Carboxyphthalato-1,2-diaminocyclohexaneplatinum
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| code | C28955
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| prefixIRI | NCIT:C28955
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| in_subset | |
| Preferred_Name | Carboxyphthalato-1,2-diaminocyclohexaneplatinum
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| FDA_UNII_Code | 918CG3EO0F
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| Contributing_Source | FDA
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| Maps_To | Dacplatinum
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| CAS_Registry | 65296-81-3
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| Legacy Concept Name | Dacplatinum
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| Semantic_Type |
Pharmacologic Substance
Inorganic Chemical
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| UMLS_CUI | C0054768
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