Preferred Name |
Cholestyramine |
|
Synonyms |
|
|
Definitions |
An anion exchange resin with hypolipidemic activity. Cholestyramine resin adsorbs and combines with bile acids in the intestine to form an insoluble complex, which is then excreted in the feces, resulting in an increased oxidation of cholesterol to bile acids, a decrease in low density lipoprotein in the plasma, and a decrease in serum cholesterol levels. |
|
ID |
http://purl.obolibrary.org/obo/NCIT_C28929 |
|
CAS_Registry |
11041-12-6 |
|
Chemical_Formula |
(C12H18ClN)n.(C10H10)n |
|
code |
C28929 |
|
Contributing_Source |
CTRP FDA |
|
definition |
An anion exchange resin with hypolipidemic activity. Cholestyramine resin adsorbs and combines with bile acids in the intestine to form an insoluble complex, which is then excreted in the feces, resulting in an increased oxidation of cholesterol to bile acids, a decrease in low density lipoprotein in the plasma, and a decrease in serum cholesterol levels. |
|
Display_Name |
Cholestyramine |
|
FDA_UNII_Code |
4B33BGI082 |
|
in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 |
|
label |
Cholestyramine |
|
Legacy Concept Name |
Cholestyramine |
|
NSC Number |
177361 |
|
Preferred_Name |
Cholestyramine |
|
prefixIRI |
NCIT:C28929 |
|
prefLabel |
Cholestyramine |
|
Semantic_Type |
Pharmacologic Substance |
|
UMLS_CUI |
C0008402 |
|
subClassOf |