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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
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| Preferred Name | Azaserine | |
| Synonyms |
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| Definitions |
A naturally occurring serine derivative diazo compound with antineoplastic properties, Azaserine functions as a purine antagonist and glutamine analogue (glutamine amidotransferase inhibitor) that competitively inhibits pathways in which glutamine is metabolized. An antibiotic and antitumor agent, Azaserine is used in clinical studies as a potential antineoplastic agent. (NCI04) |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C289 |
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| CAS_Registry |
115-02-6
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| Chemical_Formula |
C5H7N3O4
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|
| code |
C289
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| Contributing_Source |
FDA
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| definition |
A naturally occurring serine derivative diazo compound with antineoplastic properties, Azaserine functions as a purine antagonist and glutamine analogue (glutamine amidotransferase inhibitor) that competitively inhibits pathways in which glutamine is metabolized. An antibiotic and antitumor agent, Azaserine is used in clinical studies as a potential antineoplastic agent. (NCI04)
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| FDA_UNII_Code |
87299V3Q9W
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| in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C177537 http://purl.obolibrary.org/obo/NCIT_C176424 http://purl.obolibrary.org/obo/NCIT_C128784 |
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| Is_Value_For_GDC_Property | ||
| label |
Azaserine
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| Legacy Concept Name |
Azaserine
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|
| Maps_To |
Azaserine
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| NCI_Drug_Dictionary_ID |
39156
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| NSC Number |
742
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| PDQ_Closed_Trial_Search_ID |
39156
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| PDQ_Open_Trial_Search_ID |
39156
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| Preferred_Name |
Azaserine
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| prefixIRI |
NCIT:C289
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| prefLabel |
Azaserine
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| Semantic_Type |
Pharmacologic Substance Nucleic Acid, Nucleoside, or Nucleotide Antibiotic
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| UMLS_CUI |
C0004480
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| subClassOf |
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