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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C289
http://purl.obolibrary.org/obo/NCIT_C289
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|---|---|
| Preferred Name | Azaserine |
| Definitions |
A naturally occurring serine derivative diazo compound with antineoplastic properties, Azaserine functions as a purine antagonist and glutamine analogue (glutamine amidotransferase inhibitor) that competitively inhibits pathways in which glutamine is metabolized. An antibiotic and antitumor agent, Azaserine is used in clinical studies as a potential antineoplastic agent. (NCI04)
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A naturally occurring serine derivative diazo compound with antineoplastic properties, Azaserine functions as a purine antagonist and glutamine analogue (glutamine amidotransferase inhibitor) that competitively inhibits pathways in which glutamine is metabolized. An antibiotic and antitumor agent, Azaserine is used in clinical studies as a potential antineoplastic agent. (NCI04) |
|---|---|
| prefLabel | Azaserine
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| label | Azaserine
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| PDQ_Closed_Trial_Search_ID | 39156
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| code | C289
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| prefixIRI | NCIT:C289
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| in_subset | |
| Preferred_Name | Azaserine
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| FDA_UNII_Code | 87299V3Q9W
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| Contributing_Source | FDA
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| Chemical_Formula | C5H7N3O4
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| Maps_To | Azaserine
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| CAS_Registry | 115-02-6
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| NSC Number | 742
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| NCI_Drug_Dictionary_ID | 39156
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| Legacy Concept Name | Azaserine
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 39156
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| Semantic_Type |
Pharmacologic Substance
Nucleic Acid, Nucleoside, or Nucleotide
Antibiotic
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| UMLS_CUI | C0004480
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