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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C28899
http://purl.obolibrary.org/obo/NCIT_C28899
|
|---|---|
| Preferred Name | Cyclodisone |
| Definitions |
A cyclic sulfonate ester with potential antineoplastic activity. As an alkylating agent, clyclodisone induces the formation of DNA interstrand crosslinks, DNA strand breaks, and alkali-labile lesions in the DNA of some tumor cell lines. Alkylating agents exert cytotoxic and chemotherapeutic effects by transferring alkyl groups to DNA, thereby damaging DNA and interfering with DNA synthesis and cell division. (NCI04)
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A cyclic sulfonate ester with potential antineoplastic activity. As an alkylating agent, clyclodisone induces the formation of DNA interstrand crosslinks, DNA strand breaks, and alkali-labile lesions in the DNA of some tumor cell lines. Alkylating agents exert cytotoxic and chemotherapeutic effects by transferring alkyl groups to DNA, thereby damaging DNA and interfering with DNA synthesis and cell division. (NCI04) |
|---|---|
| prefLabel | Cyclodisone
|
| label | Cyclodisone
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| code | C28899
|
| prefixIRI | NCIT:C28899
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| in_subset | |
| Preferred_Name | Cyclodisone
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| FDA_UNII_Code | 7YFV4WN79I
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| Contributing_Source | FDA
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| Maps_To | Cyclodisone
|
| CAS_Registry | 99591-73-8
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| NSC Number | 348948
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| Legacy Concept Name | Cyclodisone
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| Semantic_Type | Pharmacologic Substance
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| UMLS_CUI | C0056746
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