loading...| Preferred Name | Penicillin G Sodium | |
| Synonyms |
|
|
| Definitions |
The sodium salt form of benzylpenicillin, a semi-synthetic, broad-spectrum penicillin antibiotic with bactericidal activity. Benzylpenicillin sodium binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C28865 |
|
| CAS_Registry |
69-57-8 |
|
| CHEBI_ID |
CHEBI:51765 |
|
| Chemical_Formula |
C16H17N2O4S.Na |
|
| code |
C28865 |
|
| Contributing_Source |
FDA |
|
| definition |
The sodium salt form of benzylpenicillin, a semi-synthetic, broad-spectrum penicillin antibiotic with bactericidal activity. Benzylpenicillin sodium binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis. |
|
| FDA_UNII_Code |
YS5LY7JF4N |
|
| Has_Free_Acid_Or_Base_Form | ||
| in_subset | ||
| label |
Penicillin G Sodium |
|
| Legacy Concept Name |
Benzylpenicillin_Sodium |
|
| NSC Number |
402815 |
|
| Preferred_Name |
Penicillin G Sodium |
|
| prefixIRI |
NCIT:C28865 |
|
| prefLabel |
Penicillin G Sodium |
|
| Semantic_Type |
Pharmacologic Substance Antibiotic |
|
| UMLS_CUI |
C0037540 |
|
| subClassOf |