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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C28793
http://purl.obolibrary.org/obo/NCIT_C28793
|
|---|---|
| Preferred Name | 9H-Purine-6Thio-98D |
| Definitions |
An antimetabolite analogue of purine with antineoplastic and immuno-suppressant properties. 9H-Purine-6Thio-98D substitutes for the normal nucleoside and fraudulently incorporates into DNA and inhibits de novo purine synthesis, thereby inducing cell death. In vivo, this agent, also known as 6MP-arabinoside, may occur as a metabolite of the antineoplastic agent mercaptopurine. (NCI04)
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | An antimetabolite analogue of purine with antineoplastic and immuno-suppressant properties. 9H-Purine-6Thio-98D substitutes for the normal nucleoside and fraudulently incorporates into DNA and inhibits de novo purine synthesis, thereby inducing cell death. In vivo, this agent, also known as 6MP-arabinoside, may occur as a metabolite of the antineoplastic agent mercaptopurine. (NCI04) |
|---|---|
| prefLabel | 9H-Purine-6Thio-98D
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| label | 9H-Purine-6Thio-98D
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| code | C28793
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| prefixIRI | NCIT:C28793
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| in_subset | |
| Preferred_Name | 9H-Purine-6Thio-98D
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| Maps_To | 9H-Purine-6Thio-98D
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| Legacy Concept Name | _9H-Purine-6Thio-98D
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| Semantic_Type |
Pharmacologic Substance
Nucleic Acid, Nucleoside, or Nucleotide
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| UMLS_CUI | C1515473
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