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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C28580
http://purl.obolibrary.org/obo/NCIT_C28580
|
|---|---|
| Preferred Name | Agatolimod Sodium |
| Definitions |
The tricosasodium salt of a synthetic 24-mer oligonucleotide containing 3 CpG motifs with potential antineoplastic and immunostimulatory activity. Agatolimod selectively targets Toll-like receptor 9 (TLR9), thereby activating dendritic and B cells and stimulating cytotoxic T cell and antibody responses against tumor cells bearing tumor antigens.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | The tricosasodium salt of a synthetic 24-mer oligonucleotide containing 3 CpG motifs with potential antineoplastic and immunostimulatory activity. Agatolimod selectively targets Toll-like receptor 9 (TLR9), thereby activating dendritic and B cells and stimulating cytotoxic T cell and antibody responses against tumor cells bearing tumor antigens. |
|---|---|
| prefLabel | Agatolimod Sodium
|
| label | Agatolimod Sodium
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| PDQ_Closed_Trial_Search_ID | 38660
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| code | C28580
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| Has_Target | |
| prefixIRI | NCIT:C28580
|
| in_subset |
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| Display_Name | Agatolimod Sodium
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| Preferred_Name | Agatolimod Sodium
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| FDA_UNII_Code | I4Z5C8FM6H
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| Contributing_Source |
CTRP
FDA
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| Maps_To | Agatolimod Sodium
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| CAS_Registry | 541547-35-7
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| NSC Number | 731581
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| NCI_Drug_Dictionary_ID | 38660
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| Legacy Concept Name | CpG_7909
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| type | |
| ALT_DEFINITION | A substance that is being studied in the treatment of some types of cancer. It belongs to the family of drugs called biological response modifiers.
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| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 38660
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| Semantic_Type |
Pharmacologic Substance
Nucleic Acid, Nucleoside, or Nucleotide
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| UMLS_CUI | C1436331
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