loading...| Preferred Name |
MAX-Interacting Protein 1 |
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| Synonyms |
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|
| Definitions |
Max-interacting protein 1 (228 aa, ~26 kDa) is encoded by the human MXI1 gene. This protein plays a role in transcription factor binding and transcriptional repression. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C28556 |
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| code |
C28556 |
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| definition |
Max-interacting protein 1 (228 aa, ~26 kDa) is encoded by the human MXI1 gene. This protein plays a role in transcription factor binding and transcriptional repression. |
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| DesignNote |
MAX Interacting Protein 1, encoded by the MXI1 gene, is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. |
|
| label |
MAX-Interacting Protein 1 |
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| Legacy Concept Name |
MAX_Interacting_Protein-1 |
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| OMIM_Number |
600020 |
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| Preferred_Name |
MAX-Interacting Protein 1 |
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| prefixIRI |
NCIT:C28556 |
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| prefLabel |
MAX-Interacting Protein 1 |
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| Semantic_Type |
Amino Acid, Peptide, or Protein |
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| Swiss_Prot |
P50539 |
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| UMLS_CUI |
C0212908 |
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| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://purl.obolibrary.org/obo/PR_000010793 | EFO | LOOM | |
| http://purl.obolibrary.org/obo/PR_000010793 | OBA | LOOM | |
| http://purl.bioontology.org/ontology/OMIM/600020 | OMIM | LOOM | |
| http://purl.obolibrary.org/obo/PR_000010793 | PR | LOOM | |
| http://purl.obolibrary.org/obo/PR_000010793 | NIFSTD | LOOM | |
| http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28556 | NCIT | LOOM |