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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C2844
http://purl.obolibrary.org/obo/NCIT_C2844
|
|---|---|
| Preferred Name | Actinomycin F1 |
| Definitions |
A chromopeptide antineoplastic antibiotic isolated from the bacterium Streptomyces chrysomallus. Actinomycin F1 intercalates into the minor groove of DNA and binds to topoisomerase II, leading to the inhibition of DNA replication and RNA and protein synthesis. (NCI04)
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A chromopeptide antineoplastic antibiotic isolated from the bacterium Streptomyces chrysomallus. Actinomycin F1 intercalates into the minor groove of DNA and binds to topoisomerase II, leading to the inhibition of DNA replication and RNA and protein synthesis. (NCI04) |
|---|---|
| prefLabel | Actinomycin F1
|
| label | Actinomycin F1
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| code | C2844
|
| prefixIRI | NCIT:C2844
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| in_subset | |
| Preferred_Name | Actinomycin F1
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| FDA_UNII_Code | D8HJS52NSZ
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| Contributing_Source | FDA
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| Maps_To | Actinomycin F1
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| CAS_Registry | 1402-44-4
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| Legacy Concept Name | Actinomycin_F1
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| Semantic_Type |
Amino Acid, Peptide, or Protein
Pharmacologic Substance
Antibiotic
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| UMLS_CUI | C1515876
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| Delete | Subject | Author | Type | Created |
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| No notes to display |