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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
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Preferred Name | Endothelin Receptor Type A Antagonist | |
Synonyms |
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Definitions |
A group of agents that bind to the endothelin-1 receptor (primarily endothelin-A receptor, or ET-A), thereby inhibiting tumor cell proliferation and tumor associated angiogenesis. (NCI04) |
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ID |
http://purl.obolibrary.org/obo/NCIT_C28334 |
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ALT_DEFINITION |
A substance that blocks the binding of the endothelin-1 protein to its receptor. Endothelin-1 is a small molecule that causes changes in blood vessels and helps regulate blood pressure. It can also stimulate the growth of some types of cells.
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code |
C28334
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definition |
A group of agents that bind to the endothelin-1 receptor (primarily endothelin-A receptor, or ET-A), thereby inhibiting tumor cell proliferation and tumor associated angiogenesis. (NCI04)
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label |
Endothelin Receptor Type A Antagonist
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Legacy Concept Name |
Endothelin-1_Protein_Receptor_Antagonist
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Preferred_Name |
Endothelin Receptor Type A Antagonist
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prefixIRI |
NCIT:C28334
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prefLabel |
Endothelin Receptor Type A Antagonist
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Semantic_Type |
Chemical Viewed Functionally
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UMLS_CUI |
C1516869
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subClassOf |
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Mapping To | Ontology | Source |
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http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28334 | NCIT | LOOM |