Biological and Environmental Research Ontology

Last uploaded: December 23, 2022
Id http://purl.obolibrary.org/obo/NCIT_C2811
http://purl.obolibrary.org/obo/NCIT_C2811
Preferred Name

Verpasep Caltespen
Definitions
A recombinant chimeric protein composed of the heat shock protein 65 (Hsp65) from Mycobacterium bovis, and the human papilloma viral (HPV) protein E7. Hsp65, similar to other members of its family of proteins, elicits a strong immune response and may be used to design vaccines against a number of different cancers. E7 protein is involved in carcinogenesis of anal and cervical tumors, and represents a tumor antigen that may be specifically targeted by lymphocytes. (NCI04)
Type http://www.w3.org/2002/07/owl#Class

All Properties

definition

A recombinant chimeric protein composed of the heat shock protein 65 (Hsp65) from Mycobacterium bovis, and the human papilloma viral (HPV) protein E7. Hsp65, similar to other members of its family of proteins, elicits a strong immune response and may be used to design vaccines against a number of different cancers. E7 protein is involved in carcinogenesis of anal and cervical tumors, and represents a tumor antigen that may be specifically targeted by lymphocytes. (NCI04)
prefLabel
Verpasep Caltespen
label
Verpasep Caltespen
PDQ_Closed_Trial_Search_ID
269165
code
C2811
Has_Target
prefixIRI
NCIT:C2811
in_subset
Display_Name
Verpasep Caltespen
Preferred_Name
Verpasep Caltespen
FDA_UNII_Code
Z7T0JI2E2I
Contributing_Source
CTRP
FDA
Maps_To
Verpasep Caltespen
CAS_Registry
295371-00-5
NSC Number
713219
NCI_Drug_Dictionary_ID
269165
Legacy Concept Name
HspE7
type
ALT_DEFINITION
A substance that is being studied in the prevention of cancer. It belongs to the family of drugs called fusion proteins.
Is_Value_For_GDC_Property
subClassOf
PDQ_Open_Trial_Search_ID
269165
Semantic_Type
Amino Acid, Peptide, or Protein
Pharmacologic Substance
UMLS_CUI
C1327844
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