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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C2714
http://purl.obolibrary.org/obo/NCIT_C2714
|
|---|---|
| Preferred Name | Anti-EGFR Monoclonal Antibody EMD 55900 |
| Definitions |
A murine monoclonal antibody targeting the epidermal growth factor receptor (EGFR) exhibiting anti-tumor activity. EMD 55900 antibody binds to the extracellular domain of EGFR close to the EGF binding domain and does not induce any tyrosine kinase activity on its own. As a result, EMD 55900 binding inhibits receptor activation by natural ligands thereby interrupting activation of downstream signaling cascade, required for tumor cell growth and proliferation.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A murine monoclonal antibody targeting the epidermal growth factor receptor (EGFR) exhibiting anti-tumor activity. EMD 55900 antibody binds to the extracellular domain of EGFR close to the EGF binding domain and does not induce any tyrosine kinase activity on its own. As a result, EMD 55900 binding inhibits receptor activation by natural ligands thereby interrupting activation of downstream signaling cascade, required for tumor cell growth and proliferation. |
|---|---|
| prefLabel | Anti-EGFR Monoclonal Antibody EMD 55900
|
| label | Anti-EGFR Monoclonal Antibody EMD 55900
|
| code | C2714
|
| Has_Target | |
| prefixIRI | NCIT:C2714
|
| in_subset | |
| Preferred_Name | Anti-EGFR Monoclonal Antibody EMD 55900
|
| Maps_To | Anti-EGFR Monoclonal Antibody EMD 55900
|
| Legacy Concept Name | EMD_55900
|
| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| Semantic_Type |
Amino Acid, Peptide, or Protein
Immunologic Factor
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| UMLS_CUI | C1512123
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