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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C2696
http://purl.obolibrary.org/obo/NCIT_C2696
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|---|---|
| Preferred Name | Iodine I 131 Ethiodized Oil |
| Definitions |
A cytotoxic radioconjugate consisting of lipiodol, an iodinated ethyl ester derived from poppy seed oil, labeled with iodine 131 (I-131). I-131 Lipiodol accumulates in hepatocellular carcinoma and hepatoblastoma tumor cells, resulting in targeted cytotoxicity to tumor cells while sparing surrounding normal cells and tissues. (NCI04)
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A cytotoxic radioconjugate consisting of lipiodol, an iodinated ethyl ester derived from poppy seed oil, labeled with iodine 131 (I-131). I-131 Lipiodol accumulates in hepatocellular carcinoma and hepatoblastoma tumor cells, resulting in targeted cytotoxicity to tumor cells while sparing surrounding normal cells and tissues. (NCI04) |
|---|---|
| prefLabel | Iodine I 131 Ethiodized Oil
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| label | Iodine I 131 Ethiodized Oil
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| PDQ_Closed_Trial_Search_ID | 38497
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| code | C2696
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| prefixIRI | NCIT:C2696
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| in_subset | |
| Preferred_Name | Iodine I 131 Ethiodized Oil
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| Maps_To | Iodine I 131 Ethiodized Oil
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| NCI_Drug_Dictionary_ID | 38497
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| Legacy Concept Name | I_131_Lipiodol
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| type | |
| ALT_DEFINITION | A radioactive substance being studied in the treatment of liver cancer. It is a form of poppy seed oil that contains iodine, some of which is the radioactive substance iodine I 131. It builds up in the blood and lymph vessels in the liver and may kill cancer cells. It is a type of radiopharmaceutical.
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| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 38497
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| Semantic_Type | Pharmacologic Substance
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| UMLS_CUI | C1527224
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