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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C2685
http://purl.obolibrary.org/obo/NCIT_C2685
|
|---|---|
| Preferred Name | Recombinant Vaccinia-TRICOM Vaccine |
| Definitions |
A vaccine consisting of recombinant vaccinia virus encoding a TRIad of COstimulatory Molecules (B7-1, ICAM-1, and LFA-3; also called TRICOM). Vaccination with recombinant vaccinia-TRICOM vaccine stimulates the host immune system to mount a non-specific T-cell response. With the addition of a tumor-associated antigen peptide, this vaccine may enhance a tumor-specific immune response.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A vaccine consisting of recombinant vaccinia virus encoding a TRIad of COstimulatory Molecules (B7-1, ICAM-1, and LFA-3; also called TRICOM). Vaccination with recombinant vaccinia-TRICOM vaccine stimulates the host immune system to mount a non-specific T-cell response. With the addition of a tumor-associated antigen peptide, this vaccine may enhance a tumor-specific immune response. |
|---|---|
| prefLabel | Recombinant Vaccinia-TRICOM Vaccine
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| label | Recombinant Vaccinia-TRICOM Vaccine
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| PDQ_Closed_Trial_Search_ID | 38659
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| code | C2685
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| prefixIRI | NCIT:C2685
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| in_subset | |
| Display_Name | Recombinant Vaccinia-TRICOM Vaccine
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| Preferred_Name | Recombinant Vaccinia-TRICOM Vaccine
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| Contributing_Source | CTRP
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| NSC Number | 708039
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| NCI_Drug_Dictionary_ID | 38659
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| Legacy Concept Name | Vaccinia-TRICOM_Vaccine
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| type | |
| ALT_DEFINITION | A cancer vaccine made with a form of a vaccinia virus that does not cause disease in humans. It is being studied in the treatment of some types of cancer. The virus is changed in the laboratory to make human proteins that may help immune cells in the body kill tumor cells.
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| subClassOf | |
| PDQ_Open_Trial_Search_ID | 38659
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| Semantic_Type |
Pharmacologic Substance
Virus
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| UMLS_CUI | C1099097
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