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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C2683
http://purl.obolibrary.org/obo/NCIT_C2683
|
|---|---|
| Preferred Name | Monoclonal Antibody D6.12 |
| Definitions |
A murine IgG2a monoclonal antibody directed against a 48 kDa antigen expressed on the cell surface of normal and malignant gastrointestinal epithelium. MoAb D6.12 has been shown to induce antibody-dependent cell-mediated cytotoxicity (ADCC). This MoAb, either alone or in combination with other immunotherapeutic agents, may have possible diagnostic or therapeutic applications in gastrointestinal cancers.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A murine IgG2a monoclonal antibody directed against a 48 kDa antigen expressed on the cell surface of normal and malignant gastrointestinal epithelium. MoAb D6.12 has been shown to induce antibody-dependent cell-mediated cytotoxicity (ADCC). This MoAb, either alone or in combination with other immunotherapeutic agents, may have possible diagnostic or therapeutic applications in gastrointestinal cancers. |
|---|---|
| prefLabel | Monoclonal Antibody D6.12
|
| label | Monoclonal Antibody D6.12
|
| PDQ_Closed_Trial_Search_ID | 38656
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| code | C2683
|
| prefixIRI | NCIT:C2683
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| in_subset | |
| Preferred_Name | Monoclonal Antibody D6.12
|
| Maps_To | Monoclonal Antibody D6.12
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| NSC Number | 641116
|
| NCI_Drug_Dictionary_ID | 38656
|
| Legacy Concept Name | Monoclonal_Antibody_D6_12
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| PubMedID_Primary_Reference | 8402627
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 38656
|
| Semantic_Type |
Amino Acid, Peptide, or Protein
Immunologic Factor
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| UMLS_CUI | C1134661
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