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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C26678
http://purl.obolibrary.org/obo/NCIT_C26678
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|---|---|
| Preferred Name | Endothelin Receptor Type A Antagonist YM598 |
| Definitions |
An orally active synthetic substituted phenylethenesulfonamide. As a selective endothelin A receptor antagonist, YM598 inhibits endothelin-mediated mechanisms involved in tumor cell growth and progression, angiogenesis, and metastasis. (NCI04)
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | An orally active synthetic substituted phenylethenesulfonamide. As a selective endothelin A receptor antagonist, YM598 inhibits endothelin-mediated mechanisms involved in tumor cell growth and progression, angiogenesis, and metastasis. (NCI04) |
|---|---|
| prefLabel | Endothelin Receptor Type A Antagonist YM598
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| label | Endothelin Receptor Type A Antagonist YM598
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| PDQ_Closed_Trial_Search_ID | 270682
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| code | C26678
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| prefixIRI | NCIT:C26678
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| in_subset | |
| Preferred_Name | Endothelin Receptor Type A Antagonist YM598
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| FDA_UNII_Code | OK6K3MDZ98
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| Contributing_Source | FDA
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| Maps_To | Endothelin Receptor Type A Antagonist YM598
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| CAS_Registry | 342005-82-7
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| NCI_Drug_Dictionary_ID | 270682
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| Legacy Concept Name | YM598
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| PubMedID_Primary_Reference | 16843458
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| type | |
| ALT_DEFINITION | A substance that is being studied as a treatment for advanced prostate cancer and for pain caused by prostate cancer that has spread to the bone. It belongs to the family of drugs called endothelin ETA receptor antagonists.
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| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 270682
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| Semantic_Type | Pharmacologic Substance
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| UMLS_CUI | C1175067
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