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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C26675
http://purl.obolibrary.org/obo/NCIT_C26675
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|---|---|
| Preferred Name | Talaporfin Sodium |
| Definitions |
An agent consisting of chlorin e6, derived from chlorophyll, and L-aspartic acid with photosensitizing activity. After intratumoral activation by light emitting diodes, taporfin sodium forms an extended high energy conformational state that generates singlet oxygen, resulting in free radical-mediated cell death. (NCI04)
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | An agent consisting of chlorin e6, derived from chlorophyll, and L-aspartic acid with photosensitizing activity. After intratumoral activation by light emitting diodes, taporfin sodium forms an extended high energy conformational state that generates singlet oxygen, resulting in free radical-mediated cell death. (NCI04) |
|---|---|
| prefLabel | Talaporfin Sodium
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| label | Talaporfin Sodium
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| PDQ_Closed_Trial_Search_ID | 258313
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| code | C26675
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| prefixIRI | NCIT:C26675
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| in_subset |
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| Display_Name | Talaporfin Sodium
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| Preferred_Name | Talaporfin Sodium
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| FDA_UNII_Code | L63605PZ70
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| Contributing_Source |
CTRP
FDA
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| Chemical_Formula | C38H37N5O9.4Na
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| Maps_To | Talaporfin Sodium
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| CAS_Registry | 220201-34-3
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| NCI_Drug_Dictionary_ID | 258313
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| Legacy Concept Name | Taporfin_Sodium
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| Has_Free_Acid_Or_Base_Form | |
| type | |
| ALT_DEFINITION | A drug used in photodynamic therapy. When absorbed by cancer cells and exposed to light, the drug becomes active and kills the cancer cells.
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| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 258313
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| Semantic_Type | Pharmacologic Substance
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| UMLS_CUI | C2350202
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