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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C26645
http://purl.obolibrary.org/obo/NCIT_C26645
|
|---|---|
| Preferred Name | Multi-neo-epitope Vaccine OSE 2101 |
| Definitions |
A proprietary cancer DNA vaccine that contains multiple natural and modified epitopes derived from the four tumor associated antigens, CEA, HER2/neu, p53, and MAGE 2/3. EP-2101 also includes CAP1-6D, a heteroclitic CEA analog, and PADRE, a proprietary universal T-cell epitope that serves to enhance the immunogenicity of the epitopes. This agent has been shown to elicit cytotoxic T-lymphocyte responses against tumor cells expressing these multiple epitopes. (NCI04)
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A proprietary cancer DNA vaccine that contains multiple natural and modified epitopes derived from the four tumor associated antigens, CEA, HER2/neu, p53, and MAGE 2/3. EP-2101 also includes CAP1-6D, a heteroclitic CEA analog, and PADRE, a proprietary universal T-cell epitope that serves to enhance the immunogenicity of the epitopes. This agent has been shown to elicit cytotoxic T-lymphocyte responses against tumor cells expressing these multiple epitopes. (NCI04) |
|---|---|
| prefLabel | Multi-neo-epitope Vaccine OSE 2101
|
| label | Multi-neo-epitope Vaccine OSE 2101
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| PDQ_Closed_Trial_Search_ID | 301640
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| code | C26645
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| prefixIRI | NCIT:C26645
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| in_subset | |
| Preferred_Name | Multi-neo-epitope Vaccine OSE 2101
|
| Maps_To | Multi-neo-epitope Vaccine OSE 2101
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| NCI_Drug_Dictionary_ID | 301640
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| Legacy Concept Name | EP-2101
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| type | |
| ALT_DEFINITION | A substance that is being studied as a treatment for cancer. It belongs to the family of drugs called cancer vaccines.
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| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 301640
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| Semantic_Type | Pharmacologic Substance
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| UMLS_CUI | C2606659
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