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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C26450
http://purl.obolibrary.org/obo/NCIT_C26450
|
|---|---|
| Preferred Name | Monoclonal Antibody GD2 Anti-Idiotype Vaccine |
| Definitions |
A class of vaccines that consist of anti-idiotype monoclonal antibodies against the tumor-associated antigen disialoganglioside GD2 with potential antineoplastic activity. Vaccination with a monoclonal antibody GD2 anti-idiotype vaccine produces an immunoglobulin response against GD2 with subsequent destruction of GD2 positive tumor cells via antibody-dependent cellular cytotoxicity (ADCC). GD2 is overexpressed in melanoma, neuroblastoma, soft tissue sarcoma, and small cell carcinoma of the lung. (NCI04)
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A class of vaccines that consist of anti-idiotype monoclonal antibodies against the tumor-associated antigen disialoganglioside GD2 with potential antineoplastic activity. Vaccination with a monoclonal antibody GD2 anti-idiotype vaccine produces an immunoglobulin response against GD2 with subsequent destruction of GD2 positive tumor cells via antibody-dependent cellular cytotoxicity (ADCC). GD2 is overexpressed in melanoma, neuroblastoma, soft tissue sarcoma, and small cell carcinoma of the lung. (NCI04) |
|---|---|
| prefLabel | Monoclonal Antibody GD2 Anti-Idiotype Vaccine
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| label | Monoclonal Antibody GD2 Anti-Idiotype Vaccine
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| PDQ_Closed_Trial_Search_ID | 257174
|
| code | C26450
|
| prefixIRI | NCIT:C26450
|
| in_subset | |
| Preferred_Name | Monoclonal Antibody GD2 Anti-Idiotype Vaccine
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| Maps_To | Monoclonal Antibody GD2 Anti-Idiotype Vaccine
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| NCI_Drug_Dictionary_ID | 257174
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| Legacy Concept Name | Monoclonal_Antibody_GD2_Anti-Idiotype_Vaccine
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 257174
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| Semantic_Type |
Pharmacologic Substance
Immunologic Factor
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| UMLS_CUI | C1328690
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