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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C26328
http://purl.obolibrary.org/obo/NCIT_C26328
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|---|---|
| Preferred Name | Growth/Differentiation Factor 8 |
| Definitions |
Growth/differentiation factor 8 (375 aa, ~43 kDa) is encoded by the human MSTN gene. This protein plays a role in the negative regulation of skeletal muscle growth.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | Growth/differentiation factor 8 (375 aa, ~43 kDa) is encoded by the human MSTN gene. This protein plays a role in the negative regulation of skeletal muscle growth. |
|---|---|
| label | Growth/Differentiation Factor 8
|
| prefLabel | Growth/Differentiation Factor 8
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| Legacy Concept Name | Growth_Differentiation_Factor-8
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| in_subset | |
| Preferred_Name | Growth/Differentiation Factor 8
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| Display_Name | Growth/Differentiation Factor 8
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| Swiss_Prot | O14793
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| DesignNote | Growth/Differentiation Factor 8 may be a treatment for cachexia in cancer patients.
The active growth factor is released from the precursor following proteolytic cleavage at arginine at amino acid position 266 which is the final amino acid in a polybasic proteolytic processing site. (EntrezGene and UniProt)
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| UMLS_CUI | C0538238
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| prefixIRI | NCIT:C26328
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| Contributing_Source | CTRP
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| subClassOf | |
| code | C26328
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| type | |
| OMIM_Number | 601788
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| Semantic_Type | Amino Acid, Peptide, or Protein
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| No notes to display |