Biological and Environmental Research Ontology

Last uploaded: December 23, 2022

Preferred Name	Interferon Alpha-2
Synonyms
Definitions	Interferon alpha-2 (188 aa, ~22 kDa) is encoded by the human IFNA2 gene. This protein is involved in antiviral defense, cell-cell signaling, and immune activation.
ID	http://purl.obolibrary.org/obo/NCIT_C26318
code	C26318
Contributing_Source	CTRP
definition	Interferon alpha-2 (188 aa, ~22 kDa) is encoded by the human IFNA2 gene. This protein is involved in antiviral defense, cell-cell signaling, and immune activation.
DesignNote	There are 3 forms of interferon alpha-2. Alpha-2a is the canonical form. Alpha-2b is the result of a SNP that has the variant amino acid Lys46Arg. Alpha-2c has the amino acid variation Lys46Arg, and an additional variation His57Arg. (UniProt)
Display_Name	Interferon Alpha-2
in_subset	http://purl.obolibrary.org/obo/NCIT_C116977 http://purl.obolibrary.org/obo/NCIT_C142800 http://purl.obolibrary.org/obo/NCIT_C142799
label	Interferon Alpha-2
Legacy Concept Name	Interferon_Alpha-2
OMIM_Number	147562
Preferred_Name	Interferon Alpha-2
prefixIRI	NCIT:C26318
prefLabel	Interferon Alpha-2
Semantic_Type	Amino Acid, Peptide, or Protein Immunologic Factor
Swiss_Prot	P01563
UMLS_CUI	C0535872
subClassOf	http://purl.obolibrary.org/obo/NCIT_C20494

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Mapping To	Ontology	Source
http://purl.jp/bio/4/id/200906014389821184	IOBC	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C26318	NCIT	LOOM
http://purl.bioontology.org/ontology/MESH/D000077190	MESH	LOOM
http://purl.bioontology.org/ontology/OMIM/147562	OMIM	LOOM
http://purl.obolibrary.org/obo/PR_000008915	PR	LOOM
http://purl.obolibrary.org/obo/PR_000008915	HOIP	LOOM
http://purl.obolibrary.org/obo/PR_000008915	CIDO	LOOM
http://purl.obolibrary.org/obo/PR_000008915	NIFSTD	LOOM