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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C26222
http://purl.obolibrary.org/obo/NCIT_C26222
|
|---|---|
| Preferred Name | Growth Factor Receptor-Bound Protein 2 |
| Definitions |
Growth factor receptor-bound protein 2 (217 aa, ~25 kDa) is encoded by the human GRB2 gene. This protein is involved in the progression of epidermal growth factor-mediated signaling pathways.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | Growth factor receptor-bound protein 2 (217 aa, ~25 kDa) is encoded by the human GRB2 gene. This protein is involved in the progression of epidermal growth factor-mediated signaling pathways. |
|---|---|
| prefLabel | Growth Factor Receptor-Bound Protein 2
|
| label | Growth Factor Receptor-Bound Protein 2
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| code | C26222
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| prefixIRI | NCIT:C26222
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| OMIM_Number | 108355
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| in_subset | |
| Display_Name | Growth Factor Receptor-Bound Protein 2
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| Preferred_Name | Growth Factor Receptor-Bound Protein 2
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| Contributing_Source | CTRP
|
| Swiss_Prot | P62993
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| Legacy Concept Name | Growth_Factor_Receptor-Bound_Protein-2
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| DesignNote | Growth factor receptor-bound protein 2 (GRB2) isoform 2 (GRB3-3) lacks the SH2 domain and acts in a dominant negative manner to inhibit epidermal growth factor signaling. (UniProt)
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| type | |
| subClassOf | |
| Semantic_Type | Amino Acid, Peptide, or Protein
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| UMLS_CUI | C1436247
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