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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C26203
http://purl.obolibrary.org/obo/NCIT_C26203
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|---|---|
| Preferred Name | Vascular Endothelial Growth Factor Receptor 3 |
| Definitions |
Vascular endothelial growth factor receptor 3 (1363 aa, ~153 kDa) is encoded by the human FLT4 gene. This protein is involved in tyrosine phosphorylation, lymph vessel formation and ligand-dependent signaling.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | Vascular endothelial growth factor receptor 3 (1363 aa, ~153 kDa) is encoded by the human FLT4 gene. This protein is involved in tyrosine phosphorylation, lymph vessel formation and ligand-dependent signaling. |
|---|---|
| prefLabel | Vascular Endothelial Growth Factor Receptor 3
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| label | Vascular Endothelial Growth Factor Receptor 3
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| code | C26203
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| prefixIRI | NCIT:C26203
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| OMIM_Number | 136352
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| in_subset | |
| Display_Name | Vascular Endothelial Growth Factor Receptor 3
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| Preferred_Name | Vascular Endothelial Growth Factor Receptor 3
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| Contributing_Source | CTRP
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| Swiss_Prot | P35916
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| Legacy Concept Name | FMS-Related_Tyrosine_Kinase-4
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| DesignNote | A type I membrane protein tyrosine kinase receptor for VEGF-C, vascular endothelial growth factor receptor 3, contains seven immunoglobulin-like C2-type domains. Vascular endothelial growth factors, working through VEGF receptor-3, promote angiogenesis and metastatic spread of cancer cells. (from Nat Med 2001. 7:151 & 186)
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| type | |
| subClassOf | |
| Semantic_Type |
Amino Acid, Peptide, or Protein
Receptor
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| UMLS_CUI | C3657407
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