Preferred Name

D(1A) Dopamine Receptor
Synonyms
Definitions

D(1A) dopamine receptor (446 aa, ~49 kDa) is encoded by the human DRD1 gene. This protein is involved in neurotransmitter-dependent G protein-coupled receptor signaling.

ID

http://purl.obolibrary.org/obo/NCIT_C26120

code

C26120

definition

D(1A) dopamine receptor (446 aa, ~49 kDa) is encoded by the human DRD1 gene. This protein is involved in neurotransmitter-dependent G protein-coupled receptor signaling.

DesignNote

Dopamine Receptor D1, encoded by the human DRD1 gene, is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. It regulates neuronal growth and development, mediates some behavioral responses, and modulates dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene.

label

D(1A) Dopamine Receptor

Legacy Concept Name

Dopamine_Receptor-D1

OMIM_Number

126449

Preferred_Name

D(1A) Dopamine Receptor

prefixIRI

NCIT:C26120

prefLabel

D(1A) Dopamine Receptor

Semantic_Type

Amino Acid, Peptide, or Protein

Receptor

Swiss_Prot

P21728

UMLS_CUI

C3711530

subClassOf

http://purl.obolibrary.org/obo/NCIT_C17066

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