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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C2600
http://purl.obolibrary.org/obo/NCIT_C2600
|
|---|---|
| Preferred Name | Yttrium Y 90 Daclizumab |
| Definitions |
A synthetic radioimmunoconjugate comprised of a humanized anti-interleukin-2 (IL-2) antibody linked to the radioisotope Yttrium 90 with potential antineoplastic activity. Daclizumab binds with high affinity to the Tac (also called CD25) subunit of the IL-2 receptor complex and inhibits the binding of IL-2, thereby blocking the IL-2-mediated activation of lymphocytes. As Yttrium Y 90 daclizumab, daclizumab delivers radiation specifically to lymphocytes that express the IL-2 receptor. (NCI04)
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A synthetic radioimmunoconjugate comprised of a humanized anti-interleukin-2 (IL-2) antibody linked to the radioisotope Yttrium 90 with potential antineoplastic activity. Daclizumab binds with high affinity to the Tac (also called CD25) subunit of the IL-2 receptor complex and inhibits the binding of IL-2, thereby blocking the IL-2-mediated activation of lymphocytes. As Yttrium Y 90 daclizumab, daclizumab delivers radiation specifically to lymphocytes that express the IL-2 receptor. (NCI04) |
|---|---|
| prefLabel | Yttrium Y 90 Daclizumab
|
| label | Yttrium Y 90 Daclizumab
|
| PDQ_Closed_Trial_Search_ID | 38097
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| code | C2600
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| Has_Target | |
| prefixIRI | NCIT:C2600
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| in_subset |
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| Display_Name | Yttrium Y 90 Daclizumab
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| Preferred_Name | Yttrium Y 90 Daclizumab
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| Contributing_Source | CTRP
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| Maps_To | Yttrium Y 90 Daclizumab
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| NCI_Drug_Dictionary_ID | 38097
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| Legacy Concept Name | Yttrium_Y_90_Daclizumab
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 38097
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| Semantic_Type |
Amino Acid, Peptide, or Protein
Pharmacologic Substance
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| UMLS_CUI | C0935688
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| Delete | Subject | Author | Type | Created |
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