Link to this page
Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C2558
http://purl.obolibrary.org/obo/NCIT_C2558
|
|---|---|
| Preferred Name | Oglufanide Disodium |
| Definitions |
The disodium salt of a synthetic form of a naturally-occurring dipeptide consisting of L-glutamic acid and L-tryptophan with potential antiangiogenic and potential immunomodulating activities. Oglufanide inhibits vascular endothelial growth factor (VEGF), which may inhibit angiogenesis. This agent has also been reported to stimulate the immune response to hepatitic C virus and intracellular bacterial infections.
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | The disodium salt of a synthetic form of a naturally-occurring dipeptide consisting of L-glutamic acid and L-tryptophan with potential antiangiogenic and potential immunomodulating activities. Oglufanide inhibits vascular endothelial growth factor (VEGF), which may inhibit angiogenesis. This agent has also been reported to stimulate the immune response to hepatitic C virus and intracellular bacterial infections. |
|---|---|
| prefLabel | Oglufanide Disodium
|
| label | Oglufanide Disodium
|
| NCI_META_CUI | CL032903
|
| PDQ_Closed_Trial_Search_ID | 43387
|
| code | C2558
|
| prefixIRI | NCIT:C2558
|
| in_subset | |
| Preferred_Name | Oglufanide Disodium
|
| FDA_UNII_Code | Q60AU1LLNU
|
| Contributing_Source | FDA
|
| Chemical_Formula | C16H17N3O5.2Na
|
| Maps_To | Oglufanide Disodium
|
| CAS_Registry | 237068-57-4
|
| NCI_Drug_Dictionary_ID | 43387
|
| Legacy Concept Name | Glufanide_Disodium
|
| Has_Free_Acid_Or_Base_Form | |
| PubMedID_Primary_Reference | 12180893
|
| type | |
| ALT_DEFINITION | An anticancer drug that belongs to the family of drugs called angiogenesis inhibitors.
|
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 43387
|
| Semantic_Type |
Amino Acid, Peptide, or Protein
Pharmacologic Substance
|
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |