loading...| Preferred Name |
Interleukin-2 Gene |
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| Synonyms |
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| Definitions |
The DNA sequence that encodes the protein cytokine interleukin-2 (IL-2). When introduced as the complementary DNA (cDNA) form into tumor cells by, for example, a genetically engineered adenovirus vector, the transfected IL-2 cDNA expresses IL-2 which may activate antitumoral natural killer cells and elicit an antitumoral cytotoxic T-cell response, resulting in an inhibition of tumor progression. (NCI04) |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C2549 |
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| code |
C2549 |
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| Contributing_Source |
CTRP |
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| definition |
The DNA sequence that encodes the protein cytokine interleukin-2 (IL-2). When introduced as the complementary DNA (cDNA) form into tumor cells by, for example, a genetically engineered adenovirus vector, the transfected IL-2 cDNA expresses IL-2 which may activate antitumoral natural killer cells and elicit an antitumoral cytotoxic T-cell response, resulting in an inhibition of tumor progression. (NCI04) |
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| Display_Name |
Interleukin-2 Gene |
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| in_subset |
http://purl.obolibrary.org/obo/NCIT_C176424 http://purl.obolibrary.org/obo/NCIT_C116977 |
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| label |
Interleukin-2 Gene |
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| Legacy Concept Name |
Interleukin-2_Gene |
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| NCI_Drug_Dictionary_ID |
38045 |
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| NCI_META_CUI |
CL448417 |
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| PDQ_Closed_Trial_Search_ID |
38045 |
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| PDQ_Open_Trial_Search_ID |
38045 |
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| Preferred_Name |
Interleukin-2 Gene |
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| prefixIRI |
NCIT:C2549 |
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| prefLabel |
Interleukin-2 Gene |
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| Semantic_Type |
Pharmacologic Substance Gene or Genome |
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| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://purl.bioontology.org/ontology/PDQ/CDR0000038045 | PDQ | LOOM | |
| http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2549 | NCIT | LOOM |