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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C2547
http://purl.obolibrary.org/obo/NCIT_C2547
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|---|---|
| Preferred Name | Monoclonal Antibody Hu3S193 |
| Definitions |
A humanized monoclonal antibody directed against the Lewis Y antigen, a tumor-associated epithelial antigen, with potential antineoplastic activity. Following binding, monoclonal antibody Hu3S193 triggers an antibody-dependent cell-mediated cytotoxicity in cells expressing Lewis Y antigen. (NCI05)
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A humanized monoclonal antibody directed against the Lewis Y antigen, a tumor-associated epithelial antigen, with potential antineoplastic activity. Following binding, monoclonal antibody Hu3S193 triggers an antibody-dependent cell-mediated cytotoxicity in cells expressing Lewis Y antigen. (NCI05) |
|---|---|
| label | Monoclonal Antibody Hu3S193
|
| prefLabel | Monoclonal Antibody Hu3S193
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| Legacy Concept Name | Monoclonal_Antibody_Hu3S193
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| in_subset | |
| Preferred_Name | Monoclonal Antibody Hu3S193
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| Is_Value_For_GDC_Property | |
| Maps_To | Monoclonal Antibody Hu3S193
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| PDQ_Open_Trial_Search_ID | 38031
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| UMLS_CUI | C0879578
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| prefixIRI | NCIT:C2547
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| NCI_Drug_Dictionary_ID | 38031
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| subClassOf | |
| code | C2547
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| type | |
| ALT_DEFINITION | A monoclonal antibody that is being studied in the treatment of some types of cancer. Monoclonal antibodies are made in the laboratory and can locate and bind to substances in the body, including cancer cells. Hu3S193 binds to the protein Lewis(y), which is found on colon, breast, lung, ovary, and prostate cancer cells.
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| PDQ_Closed_Trial_Search_ID | 38031
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| Semantic_Type |
Amino Acid, Peptide, or Protein
Immunologic Factor
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| CAS_Registry | 946415-49-2
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| Delete | Subject | Author | Type | Created |
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