Biological and Environmental Research Ontology

Last uploaded: December 23, 2022

Id	http://purl.obolibrary.org/obo/NCIT_C2494 http://purl.obolibrary.org/obo/NCIT_C2494
Preferred Name	13-Deoxydoxorubicin
Definitions	An analogue of the anthracycline antineoplastic antibiotic doxorubicin. 13-Deoxydoxorubicin intercalates DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. This agent was designed to be a non-cardiotoxic anthracycline antibiotic.
Type	http://www.w3.org/2002/07/owl#Class

definition	An analogue of the anthracycline antineoplastic antibiotic doxorubicin. 13-Deoxydoxorubicin intercalates DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. This agent was designed to be a non-cardiotoxic anthracycline antibiotic.
prefLabel	13-Deoxydoxorubicin
label	13-Deoxydoxorubicin
PDQ_Closed_Trial_Search_ID	43222
code	C2494
prefixIRI	NCIT:C2494
in_subset	http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C177537 http://purl.obolibrary.org/obo/NCIT_C176424 http://purl.obolibrary.org/obo/NCIT_C128784 http://purl.obolibrary.org/obo/NCIT_C157711 http://purl.obolibrary.org/obo/NCIT_C157712 See more See less
Preferred_Name	13-Deoxydoxorubicin
FDA_UNII_Code	1S9VO1DQG5
Contributing_Source	FDA
Maps_To	13-Deoxydoxorubicin
CAS_Registry	628290-43-7
NCI_Drug_Dictionary_ID	43222
Legacy Concept Name	GPX-100
type	http://www.w3.org/2002/07/owl#Class
ALT_DEFINITION	An anticancer drug that belongs to the family of drugs called antitumor antibiotics. It is an anthracycline.
Is_Value_For_GDC_Property	http://purl.obolibrary.org/obo/NCIT_C1909
subClassOf	http://purl.obolibrary.org/obo/NCIT_C1594
PDQ_Open_Trial_Search_ID	43222
Semantic_Type	Organic Chemical Pharmacologic Substance
UMLS_CUI	C0796383

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