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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C2490
http://purl.obolibrary.org/obo/NCIT_C2490
|
|---|---|
| Preferred Name | At 211 Monoclonal Antibody 81C6 |
| Definitions |
A radioimmunoconjugate of a human-murine chimeric IgG2 monoclonal antibody (MoAb) 81C6 labeled with an alpha-emitting radionuclide Astatine 211 (At-211), with imaging and radioimmunotherapeutic properties. MoAb 81C6 recognizes the extracellular matrix antigen tenascin (hexabrachion), which is up-regulated in gliomas and other cancers. Using MoAb 81C6 as a carrier for At-211 results in the targeted imaging and/or destruction of cells expressing tenascin.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A radioimmunoconjugate of a human-murine chimeric IgG2 monoclonal antibody (MoAb) 81C6 labeled with an alpha-emitting radionuclide Astatine 211 (At-211), with imaging and radioimmunotherapeutic properties. MoAb 81C6 recognizes the extracellular matrix antigen tenascin (hexabrachion), which is up-regulated in gliomas and other cancers. Using MoAb 81C6 as a carrier for At-211 results in the targeted imaging and/or destruction of cells expressing tenascin. |
|---|---|
| prefLabel | At 211 Monoclonal Antibody 81C6
|
| label | At 211 Monoclonal Antibody 81C6
|
| PDQ_Closed_Trial_Search_ID | 43148
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| code | C2490
|
| prefixIRI | NCIT:C2490
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| in_subset | |
| Preferred_Name | At 211 Monoclonal Antibody 81C6
|
| Maps_To | At 211 Monoclonal Antibody 81C6
|
| NCI_Drug_Dictionary_ID | 43148
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| Legacy Concept Name | At_211_Monoclonal_Antibody_81C6
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 43148
|
| Semantic_Type |
Amino Acid, Peptide, or Protein
Pharmacologic Substance
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| UMLS_CUI | C0796331
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