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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C2488
http://purl.obolibrary.org/obo/NCIT_C2488
|
|---|---|
| Preferred Name | Iodine I 131 Monoclonal Antibody 81C6 |
| Definitions |
A radioimmunoconjugate consisting of 81C6, a murine IgG2 anti-tenascin monoclonal antibody labeled with iodine 131 (I-131), with radioimaging and radioimmunotherapeutic activities. Using monoclonal antibody 81C6 as a carrier for I-131 results in the targeted imaging and/or destruction of cells expressing tenascin. Tenascin is an extracellular matrix protein which is overexpressed in gliomas and other cancers.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A radioimmunoconjugate consisting of 81C6, a murine IgG2 anti-tenascin monoclonal antibody labeled with iodine 131 (I-131), with radioimaging and radioimmunotherapeutic activities. Using monoclonal antibody 81C6 as a carrier for I-131 results in the targeted imaging and/or destruction of cells expressing tenascin. Tenascin is an extracellular matrix protein which is overexpressed in gliomas and other cancers. |
|---|---|
| prefLabel | Iodine I 131 Monoclonal Antibody 81C6
|
| label | Iodine I 131 Monoclonal Antibody 81C6
|
| PDQ_Closed_Trial_Search_ID | 43146
|
| code | C2488
|
| Has_Target | |
| prefixIRI | NCIT:C2488
|
| in_subset |
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| Display_Name | Iodine I 131 Monoclonal Antibody 81C6
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| Preferred_Name | Iodine I 131 Monoclonal Antibody 81C6
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| FDA_UNII_Code | D4E1UP3RMV
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| Contributing_Source |
CTRP
FDA
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| Maps_To | Iodine I 131 Monoclonal Antibody 81C6
|
| CAS_Registry | 1000874-23-6
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| NCI_Drug_Dictionary_ID | 43146
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| Legacy Concept Name | I_131_Monoclonal_Antibody_81C6
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 43146
|
| Semantic_Type |
Amino Acid, Peptide, or Protein
Pharmacologic Substance
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| UMLS_CUI | C0796329
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