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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C2477
http://purl.obolibrary.org/obo/NCIT_C2477
|
|---|---|
| Preferred Name | I 131 Monoclonal Antibody A33 |
| Definitions |
A radioimmunoconjugate of a humanized monoclonal antibody (MoAb) A33 labelled with Iodine 131 (I-131). MoAb A33 recognizes A33 antigen, a 43 KDa transmembrane glycoprotein of the immunoglobulin superfamily, highly and homogenously expressed in 95% of colorectal cancers, with only restricted expression in normal colonic mucosa. Using MoAb A33 as a carrier for I-131 results in the targeted imaging and/or destruction of cells expressed A33 antigen.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A radioimmunoconjugate of a humanized monoclonal antibody (MoAb) A33 labelled with Iodine 131 (I-131). MoAb A33 recognizes A33 antigen, a 43 KDa transmembrane glycoprotein of the immunoglobulin superfamily, highly and homogenously expressed in 95% of colorectal cancers, with only restricted expression in normal colonic mucosa. Using MoAb A33 as a carrier for I-131 results in the targeted imaging and/or destruction of cells expressed A33 antigen. |
|---|---|
| prefLabel | I 131 Monoclonal Antibody A33
|
| label | I 131 Monoclonal Antibody A33
|
| PDQ_Closed_Trial_Search_ID | 43095
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| code | C2477
|
| prefixIRI | NCIT:C2477
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| in_subset | |
| Preferred_Name | I 131 Monoclonal Antibody A33
|
| Maps_To | I 131 Monoclonal Antibody A33
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| NCI_Drug_Dictionary_ID | 43095
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| Legacy Concept Name | I_131_Monoclonal_Antibody_A33
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 43095
|
| Semantic_Type |
Amino Acid, Peptide, or Protein
Pharmacologic Substance
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| UMLS_CUI | C0678093
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