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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C2476
http://purl.obolibrary.org/obo/NCIT_C2476
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|---|---|
| Preferred Name | Monoclonal Antibody muJ591 |
| Definitions |
A murine IgG monoclonal antibody against the external domain of the prostate-specific membrane antigen (PSMA), overexpressed in the malignant prostate and its metastases. Although PSMA is not a biomarker of disease progression, over-expression indicates an aggressive phenotype of the prostate cancer. Radiolabelled MoAb muJ591 may be used in prostate cancer diagnosis and therapy.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A murine IgG monoclonal antibody against the external domain of the prostate-specific membrane antigen (PSMA), overexpressed in the malignant prostate and its metastases. Although PSMA is not a biomarker of disease progression, over-expression indicates an aggressive phenotype of the prostate cancer. Radiolabelled MoAb muJ591 may be used in prostate cancer diagnosis and therapy. |
|---|---|
| prefLabel | Monoclonal Antibody muJ591
|
| label | Monoclonal Antibody muJ591
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| PDQ_Closed_Trial_Search_ID | 43087
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| code | C2476
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| prefixIRI | NCIT:C2476
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| in_subset | |
| Preferred_Name | Monoclonal Antibody muJ591
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| Maps_To | Monoclonal Antibody muJ591
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| NCI_Drug_Dictionary_ID | 43087
|
| Legacy Concept Name | Monoclonal_Antibody_muJ591
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| type | |
| ALT_DEFINITION | A type of monoclonal antibody used in cancer detection or therapy. Monoclonal antibodies are laboratory-produced substances that can locate and bind to cancer cells.
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| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 43087
|
| Semantic_Type |
Amino Acid, Peptide, or Protein
Immunologic Factor
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| UMLS_CUI | C0678086
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