loading...| Preferred Name |
ACE Inhibitor |
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| Synonyms |
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|
| Definitions |
Any substance that inhibits angiotensin-converting enzyme (ACE), an enzyme that catalyzes the conversion of angiotensin I to angiotensin II. Inhibition of ACE results in a reduction in angiotensin II and angiotensin II-induced aldosterone secretion, causing vasodilation and natriuresis. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C247 |
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| Accepted_Therapeutic_Use_For |
Hypertension |
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| ALT_DEFINITION |
A drug that is used to lower blood pressure. An ACE inhibitor is a type of antihypertensive agent. A pharmaceutical agent that inhibits angiotensin-converting enzyme (ACE), which catalyzes the conversion of angiotensin I to angiotensin II. Inhibition of ACE results in a reduction in angiotensin II and angiotensin II-induced aldosterone secretion, causing vasodilation and natriuresis. It is primarily used for the reduction of proteinuria and the treatment of hypertension. |
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| CHEBI_ID |
CHEBI:35457 |
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| code |
C247 |
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| Contributing_Source |
NICHD PCDC |
|
| definition |
Any substance that inhibits angiotensin-converting enzyme (ACE), an enzyme that catalyzes the conversion of angiotensin I to angiotensin II. Inhibition of ACE results in a reduction in angiotensin II and angiotensin II-induced aldosterone secretion, causing vasodilation and natriuresis. |
|
| in_subset |
http://purl.obolibrary.org/obo/NCIT_C90259 http://purl.obolibrary.org/obo/NCIT_C174019 |
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| Is_PCDC_AML_Permissible_Value_For_Variable | ||
| label |
ACE Inhibitor |
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| Legacy Concept Name |
ACE_Inhibitor |
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| Preferred_Name |
ACE Inhibitor |
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| prefixIRI |
NCIT:C247 |
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| prefLabel |
ACE Inhibitor |
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| Semantic_Type |
Chemical Viewed Functionally |
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| UMLS_CUI |
C0003015 |
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| subClassOf |