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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C247
http://purl.obolibrary.org/obo/NCIT_C247
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|---|---|
| Preferred Name | ACE Inhibitor |
| Definitions |
Any substance that inhibits angiotensin-converting enzyme (ACE), an enzyme that catalyzes the conversion of angiotensin I to angiotensin II. Inhibition of ACE results in a reduction in angiotensin II and angiotensin II-induced aldosterone secretion, causing vasodilation and natriuresis.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | Any substance that inhibits angiotensin-converting enzyme (ACE), an enzyme that catalyzes the conversion of angiotensin I to angiotensin II. Inhibition of ACE results in a reduction in angiotensin II and angiotensin II-induced aldosterone secretion, causing vasodilation and natriuresis. |
|---|---|
| prefLabel | ACE Inhibitor
|
| label | ACE Inhibitor
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| CHEBI_ID | CHEBI:35457
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| code | C247
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| prefixIRI | NCIT:C247
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| in_subset | |
| Preferred_Name | ACE Inhibitor
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| Is_PCDC_AML_Permissible_Value_For_Variable | |
| Contributing_Source |
NICHD
PCDC
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| Legacy Concept Name | ACE_Inhibitor
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| type | |
| ALT_DEFINITION | A drug that is used to lower blood pressure. An ACE inhibitor is a type of antihypertensive agent.
A pharmaceutical agent that inhibits angiotensin-converting enzyme (ACE), which catalyzes the conversion of angiotensin I to angiotensin II. Inhibition of ACE results in a reduction in angiotensin II and angiotensin II-induced aldosterone secretion, causing vasodilation and natriuresis. It is primarily used for the reduction of proteinuria and the treatment of hypertension.
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| subClassOf | |
| Accepted_Therapeutic_Use_For | Hypertension
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| Semantic_Type | Chemical Viewed Functionally
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| UMLS_CUI | C0003015
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