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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C2440
http://purl.obolibrary.org/obo/NCIT_C2440
|
|---|---|
| Preferred Name | Iodine I 124 Monoclonal Antibody A33 |
| Definitions |
A radioimmunoconjugate of a humanized monoclonal antibody (MoAb) A33 labelled with Iodine 124 (I-124). MoAb A33 recognizes A33 antigen, a 43 KDa transmembrane glycoprotein of the immunoglobulin superfamily, highly and homogenously expressed in 95% of colorectal cancer metastases, with only restricted expression in normal colonic mucosa. I-124 MoAb A33 delivers beta particle emitting I-124 nuclide directly to metastatic colorectal tissues, thereby this agent could be used in kinetics studies or radioimmunotherapy.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A radioimmunoconjugate of a humanized monoclonal antibody (MoAb) A33 labelled with Iodine 124 (I-124). MoAb A33 recognizes A33 antigen, a 43 KDa transmembrane glycoprotein of the immunoglobulin superfamily, highly and homogenously expressed in 95% of colorectal cancer metastases, with only restricted expression in normal colonic mucosa. I-124 MoAb A33 delivers beta particle emitting I-124 nuclide directly to metastatic colorectal tissues, thereby this agent could be used in kinetics studies or radioimmunotherapy. |
|---|---|
| prefLabel | Iodine I 124 Monoclonal Antibody A33
|
| label | Iodine I 124 Monoclonal Antibody A33
|
| PDQ_Closed_Trial_Search_ID | 42707
|
| code | C2440
|
| prefixIRI | NCIT:C2440
|
| in_subset | |
| Preferred_Name | Iodine I 124 Monoclonal Antibody A33
|
| Maps_To | Iodine I 124 Monoclonal Antibody A33
|
| NCI_Drug_Dictionary_ID | 42707
|
| Legacy Concept Name | I_124_Monoclonal_Antibody_A33
|
| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 42707
|
| Semantic_Type |
Amino Acid, Peptide, or Protein
Indicator, Reagent, or Diagnostic Aid
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| UMLS_CUI | C0677678
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| Delete | Subject | Author | Type | Created |
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