Biological and Environmental Research Ontology

Last uploaded: December 23, 2022
Id http://purl.obolibrary.org/obo/NCIT_C2436
http://purl.obolibrary.org/obo/NCIT_C2436
Preferred Name

Monoclonal Antibody A1G4 Anti-Idiotype Vaccine
Definitions
An anti-idiotypic (anti-Id) rat monoclonal antibody (MoAb) that mimics the disialoganglioside GD2, a cancer-associated antigen present on melanoma, small cell lung cancer, sarcoma, neuroblastoma, and other malignancies. GD2 is a highly expressed glycosphingolipid by melanoma and other neuroectodermal tumors with only minimal expression on normal tissues. Vaccination with anti-Id A1G4 MoAb may elicit cellular and humoral immune responses against GD2 expression tumor cells.
Type http://www.w3.org/2002/07/owl#Class

All Properties

definition

An anti-idiotypic (anti-Id) rat monoclonal antibody (MoAb) that mimics the disialoganglioside GD2, a cancer-associated antigen present on melanoma, small cell lung cancer, sarcoma, neuroblastoma, and other malignancies. GD2 is a highly expressed glycosphingolipid by melanoma and other neuroectodermal tumors with only minimal expression on normal tissues. Vaccination with anti-Id A1G4 MoAb may elicit cellular and humoral immune responses against GD2 expression tumor cells.
prefLabel
Monoclonal Antibody A1G4 Anti-Idiotype Vaccine
label
Monoclonal Antibody A1G4 Anti-Idiotype Vaccine
PDQ_Closed_Trial_Search_ID
42698
code
C2436
prefixIRI
NCIT:C2436
in_subset
Preferred_Name
Monoclonal Antibody A1G4 Anti-Idiotype Vaccine
Maps_To
Monoclonal Antibody A1G4 Anti-Idiotype Vaccine
NCI_Drug_Dictionary_ID
42698
Legacy Concept Name
Monoclonal_Antibody_A1G4_Anti-Idiotype_Vaccine
type
Is_Value_For_GDC_Property
subClassOf
PDQ_Open_Trial_Search_ID
42698
Semantic_Type
Pharmacologic Substance
Immunologic Factor
UMLS_CUI
C0677670
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