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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C2432
http://purl.obolibrary.org/obo/NCIT_C2432
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|---|---|
| Preferred Name | Vitespen |
| Definitions |
An autologous cancer vaccine derived from tumor-specific gp96 heat shock proteins. Heat shock proteins chaperone peptides through the endoplasmic reticulum, are key regulators of dendritic cell maturation, migration and antigen processing, and are involved in T-cell activation. (NCI04)
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | An autologous cancer vaccine derived from tumor-specific gp96 heat shock proteins. Heat shock proteins chaperone peptides through the endoplasmic reticulum, are key regulators of dendritic cell maturation, migration and antigen processing, and are involved in T-cell activation. (NCI04) |
|---|---|
| prefLabel | Vitespen
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| label | Vitespen
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| PDQ_Closed_Trial_Search_ID | 42682
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| code | C2432
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| prefixIRI | NCIT:C2432
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| in_subset |
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| Display_Name | Vitespen
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| Preferred_Name | Vitespen
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| FDA_UNII_Code | H3598Y1TLJ
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| Contributing_Source |
CTRP
FDA
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| Maps_To | Vitespen
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| CAS_Registry | 492448-75-6
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| NSC Number | 725085
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| NCI_Drug_Dictionary_ID | 42682
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| Legacy Concept Name | Autologous_gp96_Heat_Shock_Protein_Peptide_Complex_Vaccine
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| type | |
| ALT_DEFINITION | A vaccine made from a patient's tumor cells that may help the body's immune system kill cancer cells. This vaccine is used to treat kidney cancer, a type of brain cancer called glioma, and metastatic melanoma (a type of skin cancer that has spread). It is also being studied in the treatment of other types of cancer.
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| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 42682
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| Semantic_Type |
Pharmacologic Substance
Immunologic Factor
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| UMLS_CUI | C0935952
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