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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C2423
http://purl.obolibrary.org/obo/NCIT_C2423
|
|---|---|
| Preferred Name | Recombinant Adenovirus-p53 SCH-58500 |
| Definitions |
A genetically-engineered adenovirus that contains the gene that encodes the human tumor-suppressor protein p53 with potential antineoplastic activity. Recombinant adenovirus-p53 SCH-58500 delivers p53 into tumor cells, which may result in p53-mediated cell cycle arrest and apoptosis.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A genetically-engineered adenovirus that contains the gene that encodes the human tumor-suppressor protein p53 with potential antineoplastic activity. Recombinant adenovirus-p53 SCH-58500 delivers p53 into tumor cells, which may result in p53-mediated cell cycle arrest and apoptosis. |
|---|---|
| prefLabel | Recombinant Adenovirus-p53 SCH-58500
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| label | Recombinant Adenovirus-p53 SCH-58500
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| PDQ_Closed_Trial_Search_ID | 42631
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| code | C2423
|
| prefixIRI | NCIT:C2423
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| in_subset | |
| Preferred_Name | Recombinant Adenovirus-p53 SCH-58500
|
| Maps_To | Recombinant Adenovirus-p53 SCH-58500
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| NCI_Drug_Dictionary_ID | 42631
|
| Legacy Concept Name | Recombinant_Adenovirus-p53
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| type | |
| ALT_DEFINITION | A substance that has been studied in the treatment of some types of cancer. rAd/p53 is a weakened adenovirus that carries the p53 gene into tumor cells, causing them to die. It is a type of gene therapy.
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| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 42631
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| Accepted_Therapeutic_Use_For | Primary ovarian cancer
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| Semantic_Type | Pharmacologic Substance
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| UMLS_CUI | C1514767
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