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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C2409
http://purl.obolibrary.org/obo/NCIT_C2409
|
|---|---|
| Preferred Name | Monoclonal Antibody Me1-14 F(ab')2 |
| Definitions |
The F(ab)2 fragment of Me1-14, a murine IgG2a monoclonal antibody directed against proteoglycan chondroitin sulfate-associated protein expressed by gliomas and melanomas. By binding to proteoglycan chondroitin sulfate-associated protein, monoclonal antibody Me1-14 F(ab')2 conjugated to a radioisotope may localize gliomas and melanomas when used as a tracer in radioimaging applications; in radioimmunotherapeutic applications, this agent conjugated to a radioisotope may be used to deliver targeted radiotoxicity to these tumors.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | The F(ab)2 fragment of Me1-14, a murine IgG2a monoclonal antibody directed against proteoglycan chondroitin sulfate-associated protein expressed by gliomas and melanomas. By binding to proteoglycan chondroitin sulfate-associated protein, monoclonal antibody Me1-14 F(ab')2 conjugated to a radioisotope may localize gliomas and melanomas when used as a tracer in radioimaging applications; in radioimmunotherapeutic applications, this agent conjugated to a radioisotope may be used to deliver targeted radiotoxicity to these tumors. |
|---|---|
| prefLabel | Monoclonal Antibody Me1-14 F(ab')2
|
| label | Monoclonal Antibody Me1-14 F(ab')2
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| PDQ_Closed_Trial_Search_ID | 42523
|
| code | C2409
|
| prefixIRI | NCIT:C2409
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| in_subset | |
| Preferred_Name | Monoclonal Antibody Me1-14 F(ab')2
|
| Maps_To | Monoclonal Antibody Me1-14 F(ab')2
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| NCI_Drug_Dictionary_ID | 42523
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| Legacy Concept Name | Monoclonal_Antibody_Me1-14_F_ab_2
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 42523
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| Semantic_Type |
Amino Acid, Peptide, or Protein
Immunologic Factor
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| UMLS_CUI | C0392955
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| Delete | Subject | Author | Type | Created |
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