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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C2372
http://purl.obolibrary.org/obo/NCIT_C2372
|
|---|---|
| Preferred Name | Monoclonal Antibody L6 |
| Definitions |
A murine IgG2a monoclonal antibody with potential antineoplastic activity. Monoclonal antibody L6 binds to the L6 antigen, a cell surface glycoprotein overexpressed in many carcinomas, and induces antibody-dependent cell-mediated cytotoxicity and complement-dependent cytotoxicity against L6-expressing tumor cells. This agent may be conjugated with various toxins in order to target their cytotoxic activity to tumor cells expressing the L6 antigen. (NCI04)
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A murine IgG2a monoclonal antibody with potential antineoplastic activity. Monoclonal antibody L6 binds to the L6 antigen, a cell surface glycoprotein overexpressed in many carcinomas, and induces antibody-dependent cell-mediated cytotoxicity and complement-dependent cytotoxicity against L6-expressing tumor cells. This agent may be conjugated with various toxins in order to target their cytotoxic activity to tumor cells expressing the L6 antigen. (NCI04) |
|---|---|
| label | Monoclonal Antibody L6
|
| prefLabel | Monoclonal Antibody L6
|
| Legacy Concept Name | Monoclonal_Antibody_L6
|
| in_subset | |
| Preferred_Name | Monoclonal Antibody L6
|
| Is_Value_For_GDC_Property | |
| Maps_To | Monoclonal Antibody L6
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| PDQ_Open_Trial_Search_ID | 41472
|
| UMLS_CUI | C0281019
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| prefixIRI | NCIT:C2372
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| NCI_Drug_Dictionary_ID | 41472
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| subClassOf | |
| code | C2372
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| type | |
| PDQ_Closed_Trial_Search_ID | 41472
|
| Semantic_Type |
Amino Acid, Peptide, or Protein
Immunologic Factor
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