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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C2368
http://purl.obolibrary.org/obo/NCIT_C2368
|
|---|---|
| Preferred Name | Monoclonal Antibody 14G2A |
| Definitions |
A murine monoclonal antibody directed against the ganglioside GD2 with potential antineoplastic activity. Monoclonal antibody 14G2A binds to the ganglioside GD2 and induces antibody-dependent cell mediated cytotoxicity and complement-dependent cytotoxicity against GD2-expressing tumor cells. GD2 is overexpressed in malignant melanoma, neuroblastoma, osteosarcoma, and small cell carcinoma of the lung. (NCI04)
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A murine monoclonal antibody directed against the ganglioside GD2 with potential antineoplastic activity. Monoclonal antibody 14G2A binds to the ganglioside GD2 and induces antibody-dependent cell mediated cytotoxicity and complement-dependent cytotoxicity against GD2-expressing tumor cells. GD2 is overexpressed in malignant melanoma, neuroblastoma, osteosarcoma, and small cell carcinoma of the lung. (NCI04) |
|---|---|
| prefLabel | Monoclonal Antibody 14G2A
|
| label | Monoclonal Antibody 14G2A
|
| PDQ_Closed_Trial_Search_ID | 41244
|
| code | C2368
|
| prefixIRI | NCIT:C2368
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| in_subset | |
| Preferred_Name | Monoclonal Antibody 14G2A
|
| FDA_UNII_Code | TC4U60XS42
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| Contributing_Source | FDA
|
| Maps_To | Monoclonal Antibody 14G2A
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| NSC Number | 624345
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| NCI_Drug_Dictionary_ID | 41244
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| Legacy Concept Name | Monoclonal_Antibody_14G2A
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 41244
|
| Semantic_Type |
Amino Acid, Peptide, or Protein
Pharmacologic Substance
Immunologic Factor
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| UMLS_CUI | C0280838
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| Delete | Subject | Author | Type | Created |
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