loading...| Preferred Name | Inhibin | |
| Synonyms |
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| Definitions |
Inhibins are peptide hormones, secreted by the follicular cells of the ovary and by the testis, that negatively regulate the synthesis and secretion of follicle stimulating hormone from the anterior pituitary. The detection of serum inhibins has been implicated in association with reproductive disorders, including infertility and ovarian cancers. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C2276 |
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| CAS_Registry |
57285-09-3 |
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| code |
C2276 |
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| definition |
Inhibins are peptide hormones, secreted by the follicular cells of the ovary and by the testis, that negatively regulate the synthesis and secretion of follicle stimulating hormone from the anterior pituitary. The detection of serum inhibins has been implicated in association with reproductive disorders, including infertility and ovarian cancers. |
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| DesignNote |
Both inhibin A and inhibin B are heterodimers consisting of an alpha subunit and a beta A or beta B subunit linked by disulphide bonds. Both inhibins function as negative regulators for FSH synthesis and secretion. Furthermore, serum concentrations of inhibins transit from inhibin B to inhibin A dominance during menstrual cycle. |
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| label |
Inhibin |
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| Legacy Concept Name |
Inhibin |
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| Preferred_Name |
Inhibin |
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| prefixIRI |
NCIT:C2276 |
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| prefLabel |
Inhibin |
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| Semantic_Type |
Amino Acid, Peptide, or Protein Hormone |
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| UMLS_CUI |
C0021463 |
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| subClassOf |