loading...| Preferred Name | Alkylating Agent | |
| Synonyms |
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| Definitions |
Agents that replace hydrogen atom(s) in biologically active molecules with alky radical(s), hindering proper function. Alkylating agents exhibit cytotoxic effects through the alkylation of DNA, resulting in strand cross-linking, ultimately inhibiting DNA replication and cell growth. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C223 |
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| ALT_DEFINITION |
A type of drug that is used in the treatment of cancer. It interferes with the cell's DNA and inhibits cancer cell growth. |
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| CHEBI_ID |
CHEBI:22333 |
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| code |
C223 |
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| definition |
Agents that replace hydrogen atom(s) in biologically active molecules with alky radical(s), hindering proper function. Alkylating agents exhibit cytotoxic effects through the alkylation of DNA, resulting in strand cross-linking, ultimately inhibiting DNA replication and cell growth. |
|
| label |
Alkylating Agent |
|
| Legacy Concept Name |
Alkylating_Agent |
|
| Preferred_Name |
Alkylating Agent |
|
| prefixIRI |
NCIT:C223 |
|
| prefLabel |
Alkylating Agent |
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| Semantic_Type |
Chemical Viewed Functionally |
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| UMLS_CUI |
C0002073 |
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| subClassOf |