Biological and Environmental Research Ontology

Last uploaded: December 23, 2022

Id	http://purl.obolibrary.org/obo/NCIT_C2202 http://purl.obolibrary.org/obo/NCIT_C2202
Preferred Name	Tacedinaline
Definitions	An orally bioavailable substituted benzamide derivative with potential antineoplastic activity. Tacedinaline inhibits histone deacetylation, which may result in histone hyperacetylation, followed by the induction of differentiation, the inhibition of cell proliferation, and apoptosis in susceptible tumor cell populations.
Type	http://www.w3.org/2002/07/owl#Class

definition	An orally bioavailable substituted benzamide derivative with potential antineoplastic activity. Tacedinaline inhibits histone deacetylation, which may result in histone hyperacetylation, followed by the induction of differentiation, the inhibition of cell proliferation, and apoptosis in susceptible tumor cell populations.
prefLabel	Tacedinaline
label	Tacedinaline
PDQ_Closed_Trial_Search_ID	37825
code	C2202
prefixIRI	NCIT:C2202
in_subset	http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C177537 http://purl.obolibrary.org/obo/NCIT_C176424 http://purl.obolibrary.org/obo/NCIT_C128784 http://purl.obolibrary.org/obo/NCIT_C157711 http://purl.obolibrary.org/obo/NCIT_C157712 See more See less
Preferred_Name	Tacedinaline
FDA_UNII_Code	UMF554N5FG
Contributing_Source	FDA
Chemical_Formula	C15H15N3O2
Maps_To	Tacedinaline
CAS_Registry	112522-64-2
NCI_Drug_Dictionary_ID	37825
Legacy Concept Name	Acetyldinaline
PubMedID_Primary_Reference	18497959
type	http://www.w3.org/2002/07/owl#Class
ALT_DEFINITION	A substance being studied in the treatment of non-small cell lung cancer.
Is_Value_For_GDC_Property	http://purl.obolibrary.org/obo/NCIT_C1909
subClassOf	http://purl.obolibrary.org/obo/NCIT_C1946
PDQ_Open_Trial_Search_ID	37825
Semantic_Type	Organic Chemical Pharmacologic Substance
UMLS_CUI	C0217598

Delete	Subject	Author	Type	Created
No notes to display