Link to this page
Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
Jump to:
| Preferred Name | Alfentanil Hydrochloride | |
| Synonyms |
|
|
| Definitions |
The hydrochloride salt of alfentanil, a synthetic short-acting opioid with analgesic and local anesthesia enhancing activity. Alfentanil primarily binds to mu-opioid receptor, a G-protein-coupled receptor, thereby mimicking the actions of morphine, the prototypical mu receptor agonist. This agent induces anti-nociception responses mediated through inhibiting the release of various neurotransmitters such as substance P, GABA, dopamine, acetylcholine and noradrenaline; in addition, the release of vasopressin, somatostatin, insulin and glucagon are also inhibited. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C220 |
|
| CAS_Registry |
70879-28-6
|
|
| Chemical_Formula |
C21H32N6O3.ClH.H2O
|
|
| code |
C220
|
|
| Contributing_Source |
FDA
|
|
| definition |
The hydrochloride salt of alfentanil, a synthetic short-acting opioid with analgesic and local anesthesia enhancing activity. Alfentanil primarily binds to mu-opioid receptor, a G-protein-coupled receptor, thereby mimicking the actions of morphine, the prototypical mu receptor agonist. This agent induces anti-nociception responses mediated through inhibiting the release of various neurotransmitters such as substance P, GABA, dopamine, acetylcholine and noradrenaline; in addition, the release of vasopressin, somatostatin, insulin and glucagon are also inhibited.
|
|
| FDA_UNII_Code |
11S92G0TIW
|
|
| Has_Free_Acid_Or_Base_Form | ||
| in_subset | ||
| label |
Alfentanil Hydrochloride
|
|
| Legacy Concept Name |
Alfentanil_Hydrochloride
|
|
| NCI_Drug_Dictionary_ID |
42783
|
|
| PDQ_Closed_Trial_Search_ID |
42783
|
|
| PDQ_Open_Trial_Search_ID |
42783
|
|
| Preferred_Name |
Alfentanil Hydrochloride
|
|
| prefixIRI |
NCIT:C220
|
|
| prefLabel |
Alfentanil Hydrochloride
|
|
| Semantic_Type |
Organic Chemical Pharmacologic Substance
|
|
| UMLS_CUI |
C0002025
|
|
| subClassOf |
Add comment
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |
Create mapping