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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C2170
http://purl.obolibrary.org/obo/NCIT_C2170
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|---|---|
| Preferred Name | Orotidylate Decarboxylase Inhibitor |
| Definitions |
Any substance that inhibits orotidine 5'-phosphate decarboxylase (orotidylate decarboxylase), an enzyme that catalyzes the decarboxylation of orotidine monophosphate to form uridine monophosphate and is required for the de novo synthesis of uridine and pyrimidines. Inhibition of orotidine 5'-phosphate decarboxylase inhibits DNA, RNA, and protein synthesis.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | Any substance that inhibits orotidine 5'-phosphate decarboxylase (orotidylate decarboxylase), an enzyme that catalyzes the decarboxylation of orotidine monophosphate to form uridine monophosphate and is required for the de novo synthesis of uridine and pyrimidines. Inhibition of orotidine 5'-phosphate decarboxylase inhibits DNA, RNA, and protein synthesis. |
|---|---|
| prefLabel | Orotidylate Decarboxylase Inhibitor
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| label | Orotidylate Decarboxylase Inhibitor
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| code | C2170
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| prefixIRI | NCIT:C2170
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| Preferred_Name | Orotidylate Decarboxylase Inhibitor
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| Legacy Concept Name | Orotidylate_Decarboxylase_Inhibitor
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| type | |
| subClassOf | |
| Semantic_Type | Chemical Viewed Functionally
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| UMLS_CUI | C1518619
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