loading...| Preferred Name | Dihydrofolate Reductase Inhibitor | |
| Synonyms |
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| Definitions |
Any substance that inhibits dihydrofolate reductase, an enzyme that catalyzes the conversion of dihydrofolate to tetrahydrofolate, an essential reaction for de novo glycine and purine synthesis. Inhibition of dihydrofolate reductase interferes with DNA and protein synthesis. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C2153 |
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| code |
C2153 |
|
| definition |
Any substance that inhibits dihydrofolate reductase, an enzyme that catalyzes the conversion of dihydrofolate to tetrahydrofolate, an essential reaction for de novo glycine and purine synthesis. Inhibition of dihydrofolate reductase interferes with DNA and protein synthesis. |
|
| label |
Dihydrofolate Reductase Inhibitor |
|
| Legacy Concept Name |
Dihydrofolate_Reductase_Inhibitor |
|
| Preferred_Name |
Dihydrofolate Reductase Inhibitor |
|
| prefixIRI |
NCIT:C2153 |
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| prefLabel |
Dihydrofolate Reductase Inhibitor |
|
| Semantic_Type |
Chemical Viewed Functionally |
|
| UMLS_CUI |
C3537100 |
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| subClassOf |